Episode Description
Summary
Dr. Marschall Runge returns for a second conversation, this time about the people who will practice medicine next.
Marschall S. Runge, MD, PhD, is a practising cardiologist who spent a decade as executive vice president for medical affairs at the University of Michigan, dean of the Medical School, and CEO of Michigan Medicine — running one of America’s largest academic health systems while continuing to see patients.
He earned his PhD in cardiovascular molecular biology at Vanderbilt and his MD at Johns Hopkins, where he also completed his internal medicine residency, followed by a cardiology fellowship at Massachusetts General Hospital. He now leads a Michigan cohort combining epigenetic ageing clocks, mitochondrial inheritance, cardiorespiratory fitness, and chronic inflammation in a single dataset.
He has authored more than 195 peer-reviewed papers and holds five healthcare patents. A third nonfiction book, on epigenetic clocks and biological ageing, is in development with Forbes Books, alongside a forthcoming Substack (The Longevity Switch) and a University of Michigan MOOC on epigenetics and ageing.
Chapters
- 00:00 Introduction and guest overview
- 01:12 AI’s role in healthcare transformation
- 04:01 AI as a valuable assistant in medicine
- 05:08 Redefining medical curriculum for AI era
- 09:34 Openness of medical institutions to AI
- 11:47 Changing accreditation and certification with AI
- 16:08 Leadership in AI adoption in healthcare
- 18:39 International perspectives on AI in medicine
- 19:13 AI’s impact on radiology and diagnostics
- 21:46 AI in clinical workflows and operations
- 24:49 The evolving role of nurses with AI
- 30:37 Digital twins and clinical trials
- 33:18 Transition period and future outlook
Chapters
- 00:00 Introduction and guest overview
- 01:12 AI’s role in healthcare transformation
- 04:01 AI as a valuable assistant in medicine
- 05:08 Redefining medical curriculum for AI era
- 09:34 Openness of medical institutions to AI
- 11:47 Changing accreditation and certification with AI
- 16:08 Leadership in AI adoption in healthcare
- 18:39 International perspectives on AI in medicine
- 19:13 AI’s impact on radiology and diagnostics
- 21:46 AI in clinical workflows and operations
- 24:49 The evolving role of nurses with AI
- 30:37 Digital twins and clinical trials
- 33:18 Transition period and future outlook

